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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC4
All Species:
21.82
Human Site:
S864
Identified Species:
30
UniProt:
Q9NTJ3
Number Species:
16
Phosphosite Substitution
Charge Score:
0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NTJ3
NP_001002800.1
1288
147182
S864
K
L
L
E
E
N
V
S
A
F
K
T
E
Y
D
Chimpanzee
Pan troglodytes
XP_001157958
1288
147223
S864
K
L
L
E
E
N
V
S
A
F
K
T
E
Y
D
Rhesus Macaque
Macaca mulatta
XP_001099428
1287
147121
S863
K
L
L
E
E
N
V
S
A
F
K
T
E
Y
D
Dog
Lupus familis
XP_535848
1288
147094
S864
K
L
L
E
E
N
V
S
V
F
K
T
E
Y
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8CG47
1286
146876
S862
K
L
L
E
E
N
V
S
V
F
K
K
E
Y
D
Rat
Rattus norvegicus
Q9Z1M9
1233
143186
L808
N
E
I
A
K
K
R
L
E
F
E
N
Q
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510551
1069
122201
S691
K
Q
L
D
E
C
A
S
A
I
T
K
A
Q
V
Chicken
Gallus gallus
NP_989849
1274
145838
N835
K
E
L
E
K
V
L
N
S
Y
K
K
D
Y
E
Frog
Xenopus laevis
P50532
1290
146971
E858
K
Q
M
E
K
N
L
E
T
L
K
K
E
Y
E
Zebra Danio
Brachydanio rerio
NP_775360
1289
145687
E863
K
Q
M
E
K
S
L
E
A
Y
R
K
D
F
E
Tiger Blowfish
Takifugu rubipres
NP_001027927
1326
150958
E859
K
Q
M
E
K
S
L
E
A
F
K
K
D
Y
E
Fruit Fly
Dros. melanogaster
Q9VJE5
1690
189046
Q1200
E
L
E
E
K
L
K
Q
A
Q
Q
S
E
Q
K
Honey Bee
Apis mellifera
XP_396862
1282
148175
N801
E
Q
L
K
N
T
M
N
T
A
K
N
T
L
E
Nematode Worm
Caenorhab. elegans
Q20060
1549
176553
E877
E
D
K
Q
K
I
V
E
E
L
E
K
K
R
D
Sea Urchin
Strong. purpuratus
XP_797583
1289
146235
Q863
T
L
E
K
A
V
E
Q
A
D
K
A
Y
Q
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
S809
K
E
L
K
K
I
I
S
K
E
E
K
E
I
E
Baker's Yeast
Sacchar. cerevisiae
Q12267
1418
162171
E939
N
V
V
M
K
N
L
E
R
L
R
G
E
Y
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.3
94
N.A.
89.5
24
N.A.
67.8
75.3
76.9
67.9
66.7
20.1
45.9
29.9
48.1
Protein Similarity:
100
99.6
98.9
96.5
N.A.
94.8
47.5
N.A.
75
86.3
87.5
83.5
81.2
40.2
63.9
47.5
65.4
P-Site Identity:
100
100
100
93.3
N.A.
86.6
6.6
N.A.
33.3
33.3
40
20
40
26.6
13.3
13.3
20
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
33.3
N.A.
40
80
66.6
80
80
53.3
46.6
46.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.3
35.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.7
55.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
6
6
0
6
0
48
6
0
6
6
0
0
% A
% Cys:
0
0
0
0
0
6
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
6
0
6
0
0
0
0
0
6
0
0
18
0
36
% D
% Glu:
18
18
12
59
36
0
6
30
12
6
18
0
53
0
36
% E
% Phe:
0
0
0
0
0
0
0
0
0
42
0
0
0
6
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
6
0
0
12
6
0
0
6
0
0
0
6
0
% I
% Lys:
65
0
6
18
53
6
6
0
6
0
59
48
6
6
12
% K
% Leu:
0
42
53
0
0
6
30
6
0
18
0
0
0
6
0
% L
% Met:
0
0
18
6
0
0
6
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
6
42
0
12
0
0
0
12
0
0
6
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
30
0
6
0
0
0
12
0
6
6
0
6
18
0
% Q
% Arg:
0
0
0
0
0
0
6
0
6
0
12
0
0
6
0
% R
% Ser:
0
0
0
0
0
12
0
42
6
0
0
6
0
0
0
% S
% Thr:
6
0
0
0
0
6
0
0
12
0
6
24
6
0
6
% T
% Val:
0
6
6
0
0
12
36
0
12
0
0
0
0
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
12
0
0
6
53
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _